Nutritional Support for The Thyroid Gland
Thyroid Synergy is a formula, encapsulated product designed to be an all-in-one thyroid support product. This product provides botanical and nutritional enhancement of thyroid hormone production, peripheral conversion of T4 to T3, as well as receptor function and recognition of thyroid hormones. The non-stimulating adaptogenic botanical American ginseng (Panax quinquefolius) has been added to help control variations in cortisol, which can have profound effects on peripheral thyroid hormone conversion, as well as serum blood glucose and insulin levels, inducing dysglycemia and laying the foundation for metabolic syndrome.
Supporting Herbs: American Ginseng Root, Coleus Forskohlii (Forslean)
The non-stimulating adaptogen botanical American ginseng (Panax quinquefolius) helps control variations in cortisol, which can have profound deleterious effects on peripheral thyroid hormone conversion, as well as serum blood glucose and insulin levels, inducing dysglycemia and laying the foundation for metabolic syndrome.
Why is Coleus Forskohlii Extract Necessary for Thyroid Support?
Coleus forskohlii is necessary for several reasons. Its active constituent forskolin is a diterpene from the roots of Coleus forskohlii. Forskolin can activate the adenylate cyclase enzyme and raise cyclic AMP levels in many tissues. This is important because Thyroid Stimulating Hormone (TSH) stimulates all steps in the synthesis and secretion of T3 and T4. The first step is the binding of TSH Hormone to TSH receptors located on the basal membrane of thyroid epithelial cells, followed by elevation of cyclic AMP levels, and a subsequent cascade of phosphorylation reactions via activation of protein kinase A. The final step is the secretion of thyroid hormones T4 and T3 which again couldn’t happen without cAMP. [10] Hypothyroid patients need support in the area of fat metabolism. Coleus is known to activate these lipolysis of fats. Coleus aids in the following functions:
Inhibiting the synthesis of adipose tissue
Increasing response to lipolytic hormones which are produced in less quantity as we age
Utilizing stored fat. [10] It may also play a role in aiding the Linda Lizotte, R.D., CDN production of digestive enzymes and supporting the immune system, both being helpful for hypothyroid patients.
Tyrosine, Copper and Coleus Forskohlii
Cyclic AMP and copper, as well as tyrosine, are involved also in the production of “feel good” catecholamines such as dopamine and norepinephrine. This could be very helpful since hypothyroid patients are so susceptible to depression. [10] Cyclic AMP is also a key player in regulating steroid hormone synthesis. These hormones include estrogen, progesterone and testosterone and depend on cholesterol for their making. [10] Women with hypothyroidism can have very severe PMS.
Chromium, Zinc and Manganese
These minerals are needed for thyroid support to help control insulin since insulin blocks phosphorylation and therefore opposes the action of epinephrine and can impede thyroid hormone production. [10] Chromium also helps to control cholesterol levels that often elevate in hypothyroid patients as well as control blood sugar levels which are challenged by poor adrenal and thyroid gland health.
Folic Acid
Hypothyroidism is associated with elevation of homocysteine as well as cholesterol. Folic acid has been shown to contribute to homocysteine metabolism by improving thyroid metabolism by improving TSH response in hypothyroidism patients. Folic acid has been shown to reduce the levels of homocysteine, a harmful amino acid associated with cardiovascular issues, by converting it into less harmful substances.
N-Acetyl-L-Tyrosine and Iodine
Tyrosine and iodine are intimately involved with the synthesis of thyroxine. N-Acetyl-L-Tyrosine is much more stable and better absorbed than L-Tyrosine. Vitamin B2 supports these enzymatic conversions.
Selenium
Selenium is a key cofactor in the enzymatic conversion (D1-enzyme) of T4, thyroxine hormone, to the more active T3, triiodothyronine. Selenium also protects the thyroid gland from mercury damage and from free radical damage caused by chemicals and heavy metals.
Vitamin A, Zinc and Selenium
Studies tell us that TR (Thyroxine Receptor) an extracellular transfer protein in humans is responsible for binding both T4 and T3 with a preference for T4. This protein also binds vitamin A known to be important for Thyroid Function. [12]
Q: Can Selenium Supplementation Help Thyroiditis?
A: Thyroiditis is inflammation of the thyroid gland. The most common type is autoimmune thyroiditis, in which, for complicated reasons, the body attacks the thyroid gland, decreasing its production of thyroid hormones.
