Resveratrol Supreme (formally Resveratrol Synergy)
Exciting research continues to emerge concerning the powerful polyphenol resveratrol, which is found in peanuts, berries, the skin of red grapes, red wine, and in the Japanese knotweed plant, also known as polygonum. Resveratrol research has proven it to be a very potent antioxidant which, among other things, acts as a sirtuin activator, meaning it activates the SIRT1 gene, which is believed to provide an anti-aging effect. The polygonum source used in Resveratrol Supreme is standardized to 50% resveratrol, all in the trans form.
One negative aspect of this research is that it would be impossible to consume, from normal food sources, the amount of resveratrol proven effective. The amounts used in one successful mouse study were approximately 22.4 mg/kg body weight per day. Scaling this amount to human body weights could imply an “equivalent human dose” of 1.5 to 2.0 grams/day, however if one compensates for the fact that humans have slower metabolic rates than mice, an equivalent human dose may be closer to a range of 200 mg/day. With this in mind Resveratrol Synergy was designed as the ultimate high potency, high quality 200mg trans-resveratrol formulation.
Resveratrol Supreme is optimally formulated to include:
- Quercetin, another beneficial polyphenol, because research suggests a powerful synergism with resveratrol.
- Lecithin for enhanced absorption.
- A standardization to the trans-form of resveratrol, as only the trans-form of the molecule is capable of activating the mammalian SIRT1 gene in vitro.
Disclaimer:
††An IPSOS 2023 survey among US functional medicine practitioners, in an average month, Designs for Health is their personally most trusted practitioner supplement brand, meaning a brand that is sold by healthcare practitioners in their office.
††An Ipsos 2023 study among a random sample of 160 functional medicine practitioners including Doctor's of Osteopathic Medicine, Pharmacists, Acupuncturists, Athletic Trainers, Personal Trainers, Fitness Trainer/Coaches, Chiropractors, Integrative Medicine Specialists, Naturopathic Doctor, Homeopaths, Medical Doctors, Physical Therapists, Nurse Practitioner/Physician Assistants, Registered Nurses, Nutritionists, Massage Therapists, Occupational Therapists and Dieticians that are aware of Designs for Health and recommend supplements to their patients.
